AM-2201

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Description

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AM-2201 (1-(5-fluoropentyl)-3-(1-naphthoyl)indole) is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor.[1] It is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern University.

AM-2201 is a full agonist for cannabinoid receptors. Affinities are: with a Ki of 1.0 nM at CB1 and 2.6 nM at CB2.[4] The 4-methyl functional analog MAM-2201 probably has similar affinities.[original research?] AM-2201 has an EC50 of 38 nM for human CB1 receptors, and 58 nM for human CB2 receptors.[5] AM-2201 produces bradycardia and hypothermia in rats at doses of 0.3–3 mg/kg, comparable to the potency of JWH-018 in rats, suggesting potent cannabinoid-like activity

ChemSpider 2D Image | 1-(5-fluoropentyl)-3-(naphthalen-1-oyl)indole | C24H22FNO

1-(5-fluoropentyl)-3-(naphthalen-1-oyl)indole

  • Molecular FormulaC24H22FNO
  • Average mass359.436 Da
  • Monoisotopic mass359.168549 Da
  • ChemSpider ID24751884
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Additional information

Weight (Grams)

25 Grams, 50 Grams, 100 Grams, 500 Grams, 1000 Grams