Ephedrine Crystals

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Description

Ephedrine is a medication and stimulant.[1] It is often used to prevent low blood pressure during spinal anesthesia.[1] It has also been used for asthma, narcolepsy, and obesity but is not the preferred treatment.[1] It is of unclear benefit in nasal congestion.[1] It can be taken by mouth or by injection into a muscle, vein, or just under the skin.[1] Onset with intravenous use is fast, while injection into a muscle can take 20 minutes, and by mouth can take an hour for effect.[1] When given by injection it lasts about an hour and when taken by mouth it can last up to four hours.[1]

Common side effects include trouble sleeping, anxiety, headache, hallucinations, high blood pressure, fast heart rate, loss of appetite, and inability to urinate.[1] Serious side effects include stroke, heart attack, and abuse.[1] While likely safe in pregnancy, its use in this population is poorly studied.[2][3] Use during breastfeeding is not recommended.[3] Ephedrine works by increasing the activity of the α and β adrenergic receptors.[1]

Ephedrine was first isolated in 1885 and came into commercial use in 1926.[4][5] It is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system.[6] It is available as a generic medication.[1] The wholesale cost in the developing world is about US$0.69–1.35 per dose.[7] In the United States it is not very expensive.[8] It can normally be found in plants of the Ephedra type.[1] Dietary supplements containing ephedrine are illegal in the United States,[1] with the exception of those used in traditional Chinese medicine, where its presence is noted by má huáng.[1]

ChemSpider 2D Image | L-(-)-Ephedrine | C10H15NO

L-(-)-Ephedrine

  • Molecular Formula C10H15NO
  • Average mass 165.232 Da
  • Monoisotopic mass 165.115356 Da
  • ChemSpider ID 8935
  • defined stereocentres – 2 of 2 defined stereocentres

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Additional information

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